Tennessee Comprehensive Lung and Sleep Center offers a gateway to the frontiers of research and development in the field of pulmonary medicine.  Pharmaceutical companies ask our physicians to serve as primary investigators for their studies in the development of treatments for diseases like asthma and COPD.  Within the framework of our center, we have a research team that allows us to screen patients for immediate consideration in new and innovative therapeutic studies.

If you are interested in participating in one of our research studies, please contact our clinical research department at:

Email: DWebb@lungandsleeptn.com or Phone: (615) 431-0469

Currently Enrolling Clinical Trials at TCLS:
Oncocyte (Pulmonary Nodules)

A study to evaluate a panel of blood biomarkers for use in patients undergoing evaluation for lung cancer.


This is a post-marketing observational study comparing the cardiovascular and cerebrovascular events in COPD patients using Anoro, Incuse or Spiriva.

PT010005 (COPD):

A study to evaluate COPD exacerbations over a 52-week treatment period in patients with moderate to very severe COPD.

PT001102 (Asthma):

A study to compare the efficacy and safety of drug to Spiriva in patients with persistent asthma.

Navigator (Asthma):

A study to evaluate the efficacy and safety of drug in adults and adolescents with severe, uncontrolled asthma.

Captain (Asthma):

A study to evaluate the effects of asthma patients receiving triple therapy through a single inhaler.

Chronicle (Asthma):

Observational study of the characteristics, treatment patterns and health outcomes of individuals with severe asthma in the United States.

Dominique Webb,
Clinical Research Manager

Dominique Webb graduated with a Bachelor of Arts in English with a Creative Writing and Pre-Medicine concentration from the University of Tennessee-Knoxville in 2013. Post-graduation, Dominique pursued a career in healthcare where she holds multiple certifications such as a Certified Pharmacy Technician, AED/CPR certified, Healthcare Informatics, and Certified Clinical Research Coordinator (CCRC). She was introduced to clinical research in 2015 as an In-House Clinical Research Associate for Covance, and as a Clinical Project Associate for Fresenius Medical Care where she was involved in multiple Phase I – Phase IV studies from feasibility to study close out. Dominique is eager to utilize her knowledge and expertise to develop and manage the Clinical Research Department at Tennessee Comprehensive Lung and Sleep Center.